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Clinical trials for Reducing Agent

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43895   clinical trials with a EudraCT protocol, of which   7301   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    65 result(s) found for: Reducing Agent. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2014-005420-10 Sponsor Protocol Number: D5136C00008 Start Date*: 2015-09-22
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, double-blind, double-dummy, parallel-group, multicenter, phase IIb study to evaluate the effect of ticagrelor 10 mg and 45 mg bid versus placebo in reducing the number of days with pa...
    Medical condition: Investigating the number of days of pain in SCD patients.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006603-20 Sponsor Protocol Number: C1377T04 Start Date*: 2009-07-29
    Sponsor Name:Centocor B.V.
    Full Title: A Phase 2, 2-Part, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled, Proof-of-concept, dose-finding Study Evaluating the Efficacy and Safety of CNTO 136 Administered Subcut...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-004369-16 Sponsor Protocol Number: MJ/LPGB/12/2006 Start Date*: 2007-11-29
    Sponsor Name:St Raphael's Hospice, Surrey
    Full Title: ''Evaluation of the efficacy of 'TRANS-DERMAL NITRATE' in reducing the severity of 'death-rattle' (i.e 'terminal lung secretions' ) in patients dying from end stage malignancy''
    Medical condition: 'Death-rattle' (i.e 'terminal lung secretions') in adult patients dying from end-stage malignancy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-022290-34 Sponsor Protocol Number: 10-001 Start Date*: 2010-12-07
    Sponsor Name:Pharmecosse
    Full Title: An investigation of the efficacy of a single dose of insulin in the prevention of excessive cutaneous scarring in breast surgery patients
    Medical condition: Scarring arising from non cancer-related bilateral breast surgery
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015019-42 Sponsor Protocol Number: CNTO148JIA3001 Start Date*: 2011-05-10
    Sponsor Name:Janssen Biologics B.V.
    Full Title: A Multicenter, Double Blind, Randomized-Withdrawal Trial of Subcutaneous Golimumab, a Human Anti-TNFα Antibody, in Pediatric Subjects with Active Polyarticular Course Juvenile Idiopathic Arthritis ...
    Medical condition: Juvenile Idiopathic Arthritis (JIA)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004870 10039075 Rheumatoid arthritis and associated conditions HLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) BE (Completed) LT (Prematurely Ended) FI (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2019-002677-57 Sponsor Protocol Number: PREVAN Start Date*: 2021-11-04
    Sponsor Name:Dra. Julia Origüen Sabater
    Full Title: A phase III, multicenter, randomized, double-blind clinical trial to evaluate the efficacy and safety of oral vancomycin versus placebo in preventing relapse of Clostridioides difficile infection i...
    Medical condition: Patients at high risk of recurrence due to CDI who require hospitalization and who increase morbidity and mortality from new CDI.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10072994 Clostridium difficile infection recurrence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001054-84 Sponsor Protocol Number: 2004/W/GI/02 Start Date*: 2005-02-16
    Sponsor Name:NHS Lothian- University Hospitals Division
    Full Title: A comparison of the efficacy of dietary hydroxypropylcellulose and questran as therapeutic agents in bile acid induced diarrhoea
    Medical condition: these patients will have bile acid induced diarrhoea identified by an increased serum 7a-OH-cholestenone. and will have a history of one of 1. ileal resection 2. idiopathic bile acid diarrhoea.3. ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000958-56 Sponsor Protocol Number: 2019/375 Start Date*: 2019-08-16
    Sponsor Name:Helse Fonna
    Full Title: “Haemodynamic stability during induction of general anesthesia with propofol and remifentanil: A randomized, controlled, double-blind study comparing low vs high propofol doses.”
    Medical condition: In daily clinical work we observe a hypotensive effect and a reduction in HR when induction of general anesthesia is performed using propofol and remifentanil. It is difficult to differentiate the ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004589-21 Sponsor Protocol Number: CLNP023B12301 Start Date*: 2021-06-17
    Sponsor Name:Novartis Pharma AG
    Full Title: A multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the efficacy and safety of iptacopan (LNP023) in complement 3 glomerulopathy
    Medical condition: complement 3 glomerulopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038359 - Renal and urinary disorders 10077827 C3 glomerulopathy PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Ongoing) FR (Ongoing) GR (Ongoing) BE (Completed) CZ (Completed) ES (Ongoing) IT (Ongoing) NL (Ongoing) SK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010582-23 Sponsor Protocol Number: CNTO148ART3002 Start Date*: 2010-01-04
    Sponsor Name:Janssen Biologics B.V.
    Full Title: A Golimumab Phase 3b, Multicenter, Switch Assessment of Subcutaneous and Intravenous Efficacy in Rheumatoid Arthritis Patients Who Have Inadequate Disease Control Despite Treatment with Etanercept ...
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    12.0 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) AT (Completed) SE (Completed) GR (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-001122-18 Sponsor Protocol Number: CNTO1275ARA2001 Start Date*: 2012-06-13
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Study Evaluating the Efficacy and Safety of Ustekinumab (STELARA®) and CNTO 1959 Administered Subcutaneously in...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    15.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2017-000889-29 Sponsor Protocol Number: CLNP023X2202 Start Date*: 2018-12-13
    Sponsor Name:Novartis Pharma AG
    Full Title: An open-label, non-randomized study on efficacy, pharmacokinetics, pharmacodynamics, safety and tolerability of LNP023 in two patient populations with C3 glomerulopathy
    Medical condition: C3 glomerulopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Completed) DE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020660-37 Sponsor Protocol Number: CR3294-2-01 Start Date*: 2010-09-08
    Sponsor Name:ROTTAPHARM S.P.A.
    Full Title: A Multicenter, randomized, double blind, double dummy, placebo controlled, parallel group, phase II study on the prevention of mucositis by CR3294, orally administered for 5 days in haematological ...
    Medical condition: assessment of the effect of CR3294 in preventing oral mucositis induced by conditioning myeloablative regimens in patients undergoing high-dose chemotherapy (HDCT) and autologous HSCT.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028130 LLT
    9.1 10017981 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-004262-16 Sponsor Protocol Number: PDTMohs05 Start Date*: 2006-01-20
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A trial comparing Metvix® photodynamic therapy (PDT) followed by Mohs micrographic surgery with Mohs micrographic surgery alone for the treatment of basal cell carcinoma (BCC)
    Medical condition: Basal cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10042503 Superficial basal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004204-39 Sponsor Protocol Number: 108701 Start Date*: 2007-02-01
    Sponsor Name:GLAXO SMITHKLINE
    Full Title: A randomized, open label, multicentre study to compare the pharmaco-economic implications of an analgesia based regimen with remifentanil and a conventional sedation based regimen using propofol in...
    Medical condition: Medical and post surgical ICU patient requiring analgesia and sedation.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10039897 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004048-21 Sponsor Protocol Number: 7171L01 Start Date*: 2006-12-29
    Sponsor Name:ZAMBON GROUP
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL GROUPS STUDY ON EFFICACY AND SAFETY OF NAC 600 MG DAILY AND NAC 1200 MG DAILY AS MUCOLYTIC AGENT IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PUL...
    Medical condition: Chronic Obstructive Pulmonary Bronchitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029978 Obstructive chronic bronchitis with acute exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-000612-17 Sponsor Protocol Number: HyperplasiLNG Start Date*: Information not available in EudraCT
    Sponsor Name:University Hospital of North Norway
    Full Title: Significance of intrauterine progestogen therapy in endometrial proliferative conditions
    Medical condition: Endometrial cancer has presently become the most frequent gynaecologic malinancy in the Western World and the incidence is still increasing. In Norway a 50% increase in occurence has been observed ...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001714-24 Sponsor Protocol Number: BTA798-CL2-001 Start Date*: 2008-06-18
    Sponsor Name:Biota Scientific Management Pty Ltd
    Full Title: A Phase II, Double-Blind Placebo-Controlled Study to Determine the Prophylactic Efficacy of Oral BTA798 in an Experimental Rhinovirus Challenge Model
    Medical condition: BTA798 is an investigational drug being developed as a potential agent for treatment and prevention of the common cold.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016823-74 Sponsor Protocol Number: CDZ-PE-002 Start Date*: 2010-01-27
    Sponsor Name:Cardoz AB
    Full Title: An open pilot study to assess the effects of pemirolast on C-reactive protein levels in subjects with coronary artery disease.
    Medical condition: Cardoz AB intends to develope pemirolast as an anti-inflammatory agent. The first intended indication for the product under development is abdominal aortic aneurysm. The proposed clinical study...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000054 Abdominal aortic aneurysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003818-92 Sponsor Protocol Number: CURITIBA_TRIAL Start Date*: 2014-12-22
    Sponsor Name:Ospedale San Raffaele, UO Chirurgia Vascolare
    Full Title: CUstodiol vs RInger: whaT Is the Best Agent?
    Medical condition: Thoracoabdominal aortic aneurysm
    Disease: Version SOC Term Classification Code Term Level
    17.1 10047065 - Vascular disorders 10002882 Aortic aneurysm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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